See also: DNA Quality Control
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis
Xiaolan Guo, Yibin Deng, Yahong Lin, Wilfredo Cosme-Blanco, Suzanne Chan, Hua He, Guohua Yuan, Eric J Brown and Sandy Chang
doi: 10.1038/sj.emboj.7601893
The EMBO Journal 26, 47094719
TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo
Sachin Katyal, Sherif F El-Khamisy, Helen R Russell, Yang Li, Limei Ju, Keith W Caldecott and Peter J McKinnon
doi: 10.1038/sj.emboj.7601869
The EMBO Journal 26, 47204731
Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA
Oleg V Tsodikov, Dmitri Ivanov, Barbara Orelli, Lidija Staresincic, Ilana Shoshani, Robert Oberman, Orlando D Schärer, Gerhard Wagner and Tom Ellenberger
doi: 10.1038/sj.emboj.7601894
The EMBO Journal 26, 47684776
Anticipating chromosomal replication fork arrest: SSB targets repair DNA helicases to active forks
François Lecointe, Céline Sérèna, Marion Velten, Audrey Costes, Stephen McGovern, Jean-Christophe Meile, Jeffrey Errington, S Dusko Ehrlich, Philippe Noirot and Patrice Polard
doi: 10.1038/sj.emboj.7601848
The EMBO Journal 26, 42394251
SUMO-targeted ubiquitin ligases in genome stability
John Prudden1, Stephanie Pebernard, Grazia Raffa, Daniela A Slavin, J Jefferson P Perry, John A Tainer, Clare H McGowan and Michael N Boddy
doi: 10.1038/sj.emboj.7601838
The EMBO Journal 26, 40894101
Replication blocking lesions present a unique substrate for homologous recombination
Jordan D Ward, Louise J Barber, Mark IR Petalcorin, Judith Yanowitz and Simon J Boulton
doi: 10.1038/sj.emboj.7601766
The EMBO Journal 26, 33843396
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
Kok-Lung Chan, Phillip S North and Ian D Hickson
doi: 10.1038/sj.emboj.7601777
The EMBO Journal 26, 33973409
The FANCJ/MutL
interaction is required for correction of the cross-link response in FA-J cells
Min Peng, Rachel Litman, Jenny Xie, Sudha Sharma, Robert M Brosh Jr and Sharon B Cantor
doi: 10.1038/sj.emboj.7601754
The EMBO Journal 26, 32383249
ATMIN defines an NBS1-independent pathway of ATM signalling
Nnennaya Kanu and Axel Behrens
doi: 10.1038/sj.emboj.7601733
The EMBO Journal 26, 29332941
BRCA2 is required for neurogenesis and suppression of medulloblastoma
Pierre-Olivier Frappart, Youngsoo Lee, Jayne Lamont and Peter J McKinnon
doi: 10.1038/sj.emboj.7601703
The EMBO Journal 26, 27322742
Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres
Andreas Meier, Heike Fiegler, Purificacion Muñoz, Peter Ellis, Diane Rigler, Cordelia Langford, Maria A Blasco, Nigel Carter and Stephen P Jackson
doi: 10.1038/sj.emboj.7601719
The EMBO Journal 26, 27072718
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway
Chen Ling, Masamichi Ishiai, Abdullah Mahmood Ali, Annette L Medhurst, Kornelia Neveling, Reinhard Kalb, Zhijiang Yan, Yutong Xue, Anneke B Oostra, Arleen D Auerbach, Maureen E Hoatlin, Detlev Schindler, Hans Joenje, Johan P de Winter, Minoru Takata, Amom Ruhikanta Meetei and Weidong Wang
doi: 10.1038/sj.emboj.7601666
The EMBO Journal 26, 21042114
Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability
Massimo Bogliolo, Alex Lyakhovich, Elsa Callén, Maria Castellà, Enrico Cappelli, María J Ramírez, Amadeu Creus, Ricard Marcos, Reinhard Kalb, Kornelia Neveling, Detlev Schindler and Jordi Surrallés
doi: 10.1038/sj.emboj.7601574
The EMBO Journal 26, 13401351
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
Jiafeng Gu, Haihui Lu, Brigette Tippin, Noriko Shimazaki, Myron F Goodman and Michael R Lieber
doi: 10.1038/sj.emboj.7601559
The EMBO Journal 26, 10101023
Impaired DNA damage checkpoint response in MIF-deficient mice
Alice Nemajerova, Patricio Mena, Gunter Fingerle-Rowson, Ute M Moll and Oleksi Petrenko
doi: 10.1038/sj.emboj.7601564
The EMBO Journal 26, 987997
RecFOR proteins are essential for Pol V-mediated translesion synthesis and mutagenesis
Shingo Fujii, Asako Isogawa and Robert P Fuchs
doi: 10.1038/sj.emboj.7601474
The EMBO Journal 25, 57545763
ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling
Thomas Stiff, Sarah A Walker, Karen Cerosaletti, Aaron A Goodarzi, Eva Petermann, Pat Concannon, Mark O'Driscoll and Penny A Jeggo
doi: 10.1038/sj.emboj.7601446
The EMBO Journal 25, 57755782
Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks
Yun-Gui Yang, Amal Saidi, Pierre-Olivier Frappart, Wookee Min, Christelle Barrucand, Valérie Dumon-Jones, Jocelyne Michelon, Zdenko Herceg and Zhao-Qi Wang
doi: 10.1038/sj.emboj.7601411
The EMBO Journal 25, 55275538
POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination
Hua He, Asha S Multani, Wilfredo Cosme-Blanco, Hidetoshi Tahara, Jin Ma, Sen Pathak, Yibin Deng and Sandy Chang
doi: 10.1038/sj.emboj.7601294
The EMBO Journal 25, 51805190
The structure-specific endonuclease Mus81Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks
Katsuhiro Hanada, Magda Budzowska, Mauro Modesti, Alex Maas, Claire Wyman, Jeroen Essers and Roland Kanaar
doi: 10.1038/sj.emboj.7601344
The EMBO Journal 25, 49214932
New functions of XPC in the protection of human skin cells from oxidative damage
Mariarosaria D'Errico, Eleonora Parlanti, Massimo Teson, Bruno M Bernardes de Jesus, Paolo Degan, Angelo Calcagnile, Pawel Jaruga, Magnar Bjørås, Marco Crescenzi, Antonia M Pedrini, Jean-Marc Egly, Giovanna Zambruno, Miria Stefanini, Miral Dizdaroglu and Eugenia Dogliotti
doi: 10.1038/sj.emboj.7601277
The EMBO Journal 25, 43054315
Mechanism of RecA-mediated homologous recombination revisited by single molecule nanomanipulation
Renaud Fulconis, Judith Mine, Aurélien Bancaud, Marie Dutreix and Jean-Louis Viovy
doi: 10.1038/sj.emboj.7601260
The EMBO Journal 25, 42934304
DNA-PK autophosphorylation facilitates Artemis endonuclease activity
Aaron A Goodarzi, Yaping Yu, Enriqueta Riballo, Pauline Douglas, Sarah A Walker, Ruiqiong Ye, Christine Härer, Caterina Marchetti, Nick Morrice, Penny A Jeggo and Susan P Lees-Miller
doi: 10.1038/sj.emboj.7601255
The EMBO Journal 25, 38803889
Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks
Patrick Ryan Potts, Matthew H Porteus and Hongtao Yu
doi: 10.1038/sj.emboj.7601218
The EMBO Journal 25, 33773388
Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange
Antony W Oliver, Angela Paul, Katherine J Boxall, S Elaine Barrie, G Wynne Aherne, Michelle D Garrett, Sibylle Mittnacht and Laurence H Pearl
doi: 10.1038/sj.emboj.7601209
The EMBO Journal 25, 31793190
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA
Jeanette Ringvoll, Line M Nordstrand, Cathrine B Vågbø, Vivi Talstad, Karen Reite, Per Arne Aas, Knut H Lauritzen, Nina Beate Liabakk, Alexandra Bjørk, Richard William Doughty, Pål Ø Falnes, Hans E Krokan and Arne Klungland
doi: 10.1038/sj.emboj.7601109
The EMBO Journal 25, 21892198
ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency
Liu Cao, Sangsoo Kim, Cuiying Xiao, Rui-Hong Wang, Xavier Coumoul, Xiaoyan Wang, Wen Mei Li, Xiao Ling Xu, Joseph A De Soto, Hiroyuki Takai, Sabine Mai, Stephen J Elledge, Noboru Motoyama and Chu-Xia Deng
doi: 10.1038/sj.emboj.7601115
The EMBO Journal 25, 21672177
Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells
Helfrid Hochegger, Donniphat Dejsuphong, Toru Fukushima, Ciaran Morrison, Eiichiro Sonoda, Valérie Schreiber, Guang Yu Zhao, Alihossein Saberi, Mitsuko Masutani, Noritaka Adachi, Hideki Koyama, Gilbert de Murcia and Shunichi Takeda
doi: 10.1038/sj.emboj.7601015
The EMBO Journal 25, 13051314
SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair
Javier M Di Noia, Cristina Rada and Michael S Neuberger
doi: 10.1038/sj.emboj.7600939
The EMBO Journal 25, 585595